Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
Mouse Monoclonal Antibody to AFAP1L2
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q8N4X5 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2H6D1 |
| Isotype | Mouse IgG1 |
| Calculated MW | 91.3kDa |
| Description | AFAP1L2 (Actin Filament Associated Protein 1 Like 2) is a Protein Coding gene. GO annotations related to this gene include SH3 domain binding and protein tyrosine kinase activator activity. An important paralog of this gene is AFAP1.; |
| Immunogen | Purified recombinant fragment of human AFAP1L2 (AA: 674-818) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application Note | ELISA: 1/10000 WB: 1/500 - 1/2000 FCM: 1/200 - 1/400 |
| Gene ID | 84632 |
|---|---|
| Other Names | XB130; KIAA1914; CTB-1144G6.4 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Monoclonal Antibody to AFAP1L2 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AFAP1L2 |
|---|---|
| Synonyms | KIAA1914, XB130 |
| Function | May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1.Int J Clin Exp Pathol. 2015 May 1;8(5):5300-8. ; 2.PLoS One. 2013;8(3):e59057.;
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
