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SMARCA1
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | P28370 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2H7B8 |
| Isotype | Mouse IgG1 |
| Calculated MW | 122.6kDa |
| Immunogen | Purified recombinant fragment of human SMARCA1 (AA: 933-1070) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 6594 |
|---|---|
| Other Names | SWI; ISWI; SWI2; SNF2L; SNF2L1; SNF2LB; SNF2LT; hSNF2L; NURF140 |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~1/200 - 1/400 IHC~~ 1/200 - 1/1000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SMARCA1 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SMARCA1 |
|---|---|
| Synonyms | SNF2L, SNF2L1 |
| Function | [Isoform 1]: Catalytically inactive when either DNA or nucleosomes are the substrate and does not possess chromatin-remodeling activity (PubMed:15310751, PubMed:28801535). Acts as a negative regulator of chromatin remodelers by generating inactive complexes (PubMed:15310751). |
| Cellular Location | Nucleus. |
| Tissue Location | [Isoform 1]: Mainly expressed in non-neuronal tissues such as lung, breast, kidney, and ovary |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
1.Yonsei Med J. 2013 May 1;54(3):772-7.2.BMC Med Genet. 2008 Feb 26;9:11.
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