SMARCA1
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | P28370 |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2H7B9 |
Isotype | Mouse IgG1 |
Calculated MW | 122.6kDa |
Immunogen | Purified recombinant fragment of human SMARCA1 (AA: 933-1070) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 6594 |
---|---|
Other Names | SWI; ISWI; SWI2; SNF2L; SNF2L1; SNF2LB; SNF2LT; hSNF2L; NURF140 |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~1/200 - 1/400 IHC~~ 1/200 - 1/1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SMARCA1 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SMARCA1 |
---|---|
Synonyms | SNF2L, SNF2L1 |
Function | [Isoform 1]: Catalytically inactive when either DNA or nucleosomes are the substrate and does not possess chromatin-remodeling activity (PubMed:15310751, PubMed:28801535). Acts as a negative regulator of chromatin remodelers by generating inactive complexes (PubMed:15310751). |
Cellular Location | Nucleus. |
Tissue Location | [Isoform 1]: Mainly expressed in non-neuronal tissues such as lung, breast, kidney, and ovary |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Yonsei Med J. 2013 May 1;54(3):772-7.2.BMC Med Genet. 2008 Feb 26;9:11.
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