GRIK5
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | Q16478 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 4G5H8 |
Isotype | Mouse IgG1 |
Calculated MW | 109.3kDa |
Immunogen | Purified recombinant fragment of human GRIK5 (AA: extra 21-166) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 2901 |
---|---|
Other Names | KA2; EAA2; GRIK2; GluK5 |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GRIK5 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GRIK5 |
---|---|
Synonyms | GRIK2 |
Function | Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R- ACPD. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
1.EMBO J. 2013 Feb 20;32(4):496-510.2.Psychiatry Res. 2006 Jan 30;141(1):39-51.
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