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GRIK3
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC, E |
|---|---|
| Primary Accession | Q13003 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2B3D1 |
| Isotype | Mouse IgG1 |
| Calculated MW | 104kDa |
| Immunogen | Purified recombinant fragment of human GRIK3 (AA: extra 32-173) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Gene ID | 2899 |
|---|---|
| Other Names | EAA5; GLR7; GLUR7; GluK3; GluR7a |
| Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 ICC~~ 1/200 - 1/1000 |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GRIK3 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRIK3 |
|---|---|
| Synonyms | GLUR7 |
| Function | Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
1.Am J Med Genet A. 2014 Feb;164A(2):456-60.2.Eur Addict Res. 2013;19(1):55-9.
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