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HTR3B

Purified Mouse Monoclonal Antibody

     
  • E - HTR3B AO2625a
    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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  • WB - HTR3B AO2625a
    Figure 2:Western blot analysis using HTR3B mAb against human HTR3B (AA: extra 23-150) recombinant protein. (Expected MW is 41.1 kDa)
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  • WB - HTR3B AO2625a
    Figure 3:Western blot analysis using HTR3B mAb against HEK293 (1) and HTR3B (AA: extra 23-150)-hIgGFc transfected HEK293 (2) cell lysate.
    detail
  • WB - HTR3B AO2625a
    Figure 4:Western blot analysis using HTR3B mouse mAb against SH-SY5Y (1) and Hela (2) cell lysate.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, ICC, E
Primary Accession O95264
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4G6H7
Isotype Mouse IgG1
Calculated MW 50.3kDa
Immunogen Purified recombinant fragment of human HTR3B (AA: extra 23-150) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 9177
Other Names 5-HT3B
Dilution E~~ 1/10000
WB~~ 1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHTR3B is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR3B (HGNC:5298)
Function Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation- selective channel complexes, which when activated cause fast, depolarizing responses in neurons.
Cellular Location Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A
Tissue Location Expressed in the brain cortex, in the caudate nucleus, the hippocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta
Research Areas
Citations (0)
citation

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References

1.Yonsei Med J. 2015 Sep;56(5):1415-20.2.Psychiatry Res. 2014 Sep 30;219(1):235-7.

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$ 385.00
Cat# AO2625a
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