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C1S Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP10109c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP10109c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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C1S Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | P09871 |
| Other Accession | NP_958850.1, NP_001725.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 76684 Da |
C1S Antibody (Center) - Additional info | |
| Gene ID 716 | |
| Other Names C1S; Complement C1s subcomponent; C1 esterase; Complement component 1 subcomponent s; Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain | |
| Target/Specificity This C1S antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 354-384 amino acids from the Central region of human C1S. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions C1S Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
C1S Antibody (Center) - Protein Information | |
| Name C1S | |
| Function C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 | |
C1S Antibody (Center) - Related products
C1S Antibody (Center) - Application data
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C1S Antibody (Center) (Cat. #AP10109c) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the C1S antibody detected the C1S protein (arrow).
C1S Antibody (Center) - Research Areas
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BACKGROUND
This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq].
REFERENCES
Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Pflieger, D., et al. Mol. Cell Proteomics 9(4):593-610(2010) Cerhan, J.R., et al. Br. J. Haematol. 145(5):614-623(2009) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)
