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ABLIM1 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP10117c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP10117c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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- Backgrounds
ABLIM1 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | O14639 |
| Other Accession | NP_002304.3, NP_006711.3, NP_001003407.1, NP_001003408.1 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 87688 Da |
ABLIM1 Antibody (Center) - Additional info | |
| Gene ID 3983 | |
| Other Names ABLIM1; ABLIM; KIAA0059; LIMAB1; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1; Actin-binding double zinc finger protein; Limatin | |
| Target/Specificity This ABLIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the Central region of human ABLIM1. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABLIM1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABLIM1 Antibody (Center) - Protein Information | |
| Name ABLIM1 | |
| Synonyms ABLIM, KIAA0059, LIMAB1 | |
| Function May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance | |
| Cellular Location Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Associated with the cytoskeleton (By similarity) | |
| Tissue Location Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers | |
ABLIM1 Antibody (Center) - Related products
AP10117c: ABLIM1 Antibody (Center)
ABLIM1 Antibody (Center) - Application data
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ABLIM1 Antibody (Center) (Cat. #AP10117c) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the ABLIM1 antibody detected the ABLIM1 protein (arrow).
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ABLIM1 antibody (Center) (Cat. #AP10117c) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABLIM1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
ABLIM1 Antibody (Center) - Research Areas
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BACKGROUND
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
REFERENCES
Feng, T., et al. Hum. Genet. 128(3):269-280(2010) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Olsen, J.V., et al. Cell 127(3):635-648(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006)
