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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ACOT11 Antibody (C-term)   

ACOT11 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ACOT11 Antibody (C-term) AP10130b
    ACOT11 Antibody (C-term) (Cat. #AP10130b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ACOT11 antibody detected the ACOT11 protein (arrow).
  • IHC-P - ACOT11 Antibody (C-term) AP10130b
    ACOT11 Antibody (C-term) (Cat. #AP10130b) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ACOT11 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - ACOT11 Antibody (C-term) AP10130b
    ACOT11 Antibody (C-term) (Cat. #AP10130b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WXI4
Other Accession NP_056362.1, NP_671517.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 68492 Da
Antigen Region 549-575 aa
Additional Information
Gene ID 26027
Other Names Acyl-coenzyme A thioesterase 11, Acyl-CoA thioesterase 11, 312-, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, ACOT11, BFIT, KIAA0707, THEA
Target/Specificity This ACOT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-575 amino acids from the C-terminal region of human ACOT11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsACOT11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACOT11
Synonyms BFIT, KIAA0707, THEA
Function Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates.
Cellular Location Cytoplasm.
Tissue Location Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue
Research Areas
Citations (0)

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This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.


Kirkby, B., et al. Prog. Lipid Res. 49(4):366-377(2010)
Hunt, M.C., et al. J. Lipid Res. 46(9):2029-2032(2005)
Adams, S.H., et al. Biochem. J. 360 (PT 1), 135-142 (2001) :

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$ 295.00
$ 99.00
Cat# AP10130b
(40 western blots)
Availability: In Stock
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