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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ABCC10 Antibody (Center)   

ABCC10 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ABCC10 Antibody (Center) AP10143c
    ABCC10 Antibody (Center) (Cat. #AP10143c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ABCC10 antibody detected the ABCC10 protein (arrow).
  • IHC-P - ABCC10 Antibody (Center) AP10143c
    ABCC10 antibody (Center) (Cat. #AP10143c) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC10 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - ABCC10 Antibody (Center) AP10143c
    ABCC10 Antibody (Center) (Cat. #AP10143c) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5T3U5
Other Accession NP_258261.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 161629 Da
Antigen Region 767-793 aa
Additional Information
Gene ID 89845
Other Names Multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10, ABCC10, MRP7, SIMRP7
Target/Specificity This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 amino acids from the Central region of human ABCC10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsABCC10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCC10
Synonyms MRP7, SIMRP7
Function ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
Cellular Location Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}
Tissue Location Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.


Kuang, Y.H., et al. Biochem. Pharmacol. 79(2):154-161(2010)
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Zhou, Y., et al. Biochem. Pharmacol. 77(6):993-1001(2009)
Hopper-Borge, E., et al. Cancer Res. 69(1):178-184(2009)
Shen, T., et al. PLoS ONE 4 (10), E7520 (2009) :

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Cat# AP10143c
(40 western blots)
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