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ABCC10 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP10143c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP10143c-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ABCC10 Antibody (Center) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | Q5T3U5 |
| Other Accession | NP_258261.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 161629 Da |
ABCC10 Antibody (Center) - Additional info | |
| Gene ID 89845 | |
| Other Names ABCC10; MRP7; SIMRP7; Multidrug resistance-associated protein 7; ATP-binding cassette sub-family C member 10 | |
| Target/Specificity This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-801 amino acids from the Central region of human ABCC10. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABCC10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABCC10 Antibody (Center) - Protein Information | |
| Name ABCC10 | |
| Synonyms MRP7, SIMRP7 | |
| Function ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion | |
| Cellular Location Cell membrane; Multi-pass membrane protein. | |
| Tissue Location Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed | |
ABCC10 Antibody (Center) - Related products
ABCC10 Antibody (Center) - Application data
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ABCC10 Antibody (Center) (Cat. #AP10143c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ABCC10 antibody detected the ABCC10 protein (arrow).
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ABCC10 antibody (Center) (Cat. #AP10143c) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC10 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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ABCC10 Antibody (Center) (Cat. #AP10143c) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ABCC10 Antibody (Center) - Research Areas
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BACKGROUND
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Kuang, Y.H., et al. Biochem. Pharmacol. 79(2):154-161(2010) Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009) Zhou, Y., et al. Biochem. Pharmacol. 77(6):993-1001(2009) Hopper-Borge, E., et al. Cancer Res. 69(1):178-184(2009) Shen, T., et al. PLoS ONE 4 (10), E7520 (2009) :
