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ABI3 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP10155a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP10155a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ABI3 Antibody (N-term) - Product info | |
| Application | WB, FC
|
| Primary Accession | Q9P2A4 |
| Other Accession | NP_057512.1, NP_001128658.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 39035 Da |
ABI3 Antibody (N-term) - Additional info | |
| Gene ID 51225 | |
| Other Names ABI3; NESH; ABI gene family member 3; New molecule including SH3 | |
| Target/Specificity This ABI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ABI3. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABI3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABI3 Antibody (N-term) - Protein Information | |
| Name ABI3 | |
| Synonyms NESH | |
| Function May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility | |
| Cellular Location Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells | |
| Tissue Location Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle | |
ABI3 Antibody (N-term) - Related products
AP10155a: ABI3 Antibody (N-term)
ABI3 Antibody (N-term) - Application data
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ABI3 Antibody (N-term) (Cat. #AP10155a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ABI3 antibody detected the ABI3 protein (arrow).
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ABI3 Antibody (N-term) (Cat. #AP10155a) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ABI3 Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates Rac-dependent actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.
REFERENCES
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009) Hirao, N., et al. FEBS Lett. 580(27):6464-6470(2006) Ichigotani, Y., et al. Int. J. Mol. Med. 9(6):591-595(2002) Ichigotani, Y., et al. Cancer Res. 62(8):2215-2219(2002) Matsuda, S., et al. J. Hum. Genet. 46(8):483-486(2001)
