|Application ||WB, FC, E|
|Calculated MW||177127 Da|
|Antigen Region||5-34 aa|
|Other Names||DNA excision repair protein ERCC-6-like 2, 364-, DNA repair and recombination protein RAD26-like, ERCC6L2, C9orf102, RAD26L|
|Target/Specificity||This RAD26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-34 amino acids from the N-terminal region of human RAD26.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAD26 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in early DNA damage response.|
|Cellular Location||Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mitochondrion Note=Colocalizes with NEK6 in the centrosome. In response to DNA damage, translocates from the cytosol to mitochondria and nucleus in a reactive oxygen species (ROS)-dependent manner|
|Tissue Location||Expressed in bone marrow (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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