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G0S2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - G0S2 Antibody (Center) AP10188c
    G0S2 Antibody (Center) (Cat. #AP10188c) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the G0S2 antibody detected G0S2 protein (arrow).
    detail
  • WB - G0S2 Antibody (Center) AP10188c
    G0S2 Antibody (Center) (Cat. #AP10188c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the G0S2 antibody detected the G0S2 protein (arrow).
    detail
  • IHC-P - G0S2 Antibody (Center) AP10188c
    G0S2 antibody (Center) (Cat. #AP10188c) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the G0S2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P27469
Other Accession NP_056529.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 11321 Da
Antigen Region 36-62 aa
Additional Information
Gene ID 50486
Other Names G0/G1 switch protein 2, G0/G1 switch regulatory protein 2, Putative lymphocyte G0/G1 switch gene, G0S2
Target/Specificity This G0S2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-62 amino acids from the Central region of human G0S2.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsG0S2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name G0S2
Function Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
Cellular Location Mitochondrion.
Tissue Location Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver
Research Areas
Citations (0)
citation

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References

Kusakabe, M., et al. Int. J. Cancer 126(8):1895-1902(2010)
Kusakabe, M., et al. Biochem. Biophys. Res. Commun. 390(4):1283-1287(2009)
Welch, C., et al. Cancer Res. 69(17):6782-6789(2009)
Kitareewan, S., et al. Int. J. Oncol. 33(2):397-404(2008)
Zandbergen, F., et al. Biochem. J. 392 (PT 2), 313-324 (2005) :

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Discontinued
Cat# AP10188c
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