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EXOC8 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IYI6 |
| Other Accession | NP_787072.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 81799 Da |
| Antigen Region | 360-389 aa |
| Gene ID | 149371 |
|---|---|
| Other Names | Exocyst complex component 8, Exocyst complex 84 kDa subunit, EXOC8 |
| Target/Specificity | This EXOC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-389 amino acids from the Central region of human EXOC8. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EXOC8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EXOC8 |
|---|---|
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O54924}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54924}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54924}. Cell projection {ECO:0000250|UniProtKB:O54924}. Note=Perinuclear in undifferentiated PC12 cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). Binds lipids with phosphatidylinositol 3,4,5-trisphosphate groups (By similarity) Localizes at the leading edge of migrating cells (By similarity) {ECO:0000250, ECO:0000250|UniProtKB:O54924} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Issaq, S.H., et al. Mol. Cancer Res. 8(2):223-231(2010)
Moskalenko, S., et al. J. Biol. Chem. 278(51):51743-51748(2003)
Wang, S., et al. Hybrid. Hybridomics 22(3):159-164(2003)
Inoue, M., et al. Nature 422(6932):629-633(2003)
Brymora, A., et al. J. Biol. Chem. 276(32):29792-29797(2001)
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