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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GGTLC2 Antibody (Center)   

GGTLC2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GGTLC2 Antibody (Center) AP10216C
    GGTLC2 Antibody (Center) (Cat. #AP10216c) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the GGTLC2 antibody detected the GGTLC2 protein (arrow).
  • IHC-P - GGTLC2 Antibody (Center) AP10216C
    GGTLC2 antibody (Center) (Cat. #AP10216c) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GGTLC2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - GGTLC2 Antibody (Center) AP10216C
    GGTLC2 Antibody (Center) (Cat. #AP10216c) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14390
Other Accession B5MD39, A6NGU5, P36268, P07314, P20735, Q60928, P19440, NP_954578.2
Reactivity Human
Predicted Mouse, Pig, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23661 Da
Antigen Region 127-154 aa
Additional Information
Gene ID 91227
Other Names Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTLC2, GGTL4
Target/Specificity This GGTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human GGTLC2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGGTLC2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GGTL4
Tissue Location Placenta and sigmoid tissues.
Research Areas
Citations (0)

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Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM].


Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)
Dunham, I., et al. Nature 402(6761):489-495(1999)
Kawasaki, K., et al. Genome Res. 7(3):250-261(1997)
Leh, H., et al. FEBS Lett. 394(3):258-262(1996)
Wetmore, L.A., et al. Proc. Natl. Acad. Sci. U.S.A. 90(16):7461-7465(1993)

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Cat# AP10216C
(40 western blots)
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