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QCR8 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP10227b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP10227b-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
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  • Backgrounds

QCR8 Antibody (C-term) - Product info

ApplicationWB, IHC, FC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionO14949
Other AccessionNP_055217.2
ReactivityHuman, Mouse
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW9906 Da

QCR8 Antibody (C-term) - Additional info

Gene ID 27089
Other Names
UQCRQ; Cytochrome b-c1 complex subunit 8; Complex III subunit 8; Complex III subunit VIII; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
Target/Specificity
This QCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the C-terminal region of human QCR8.
Dilution
WB~~1:100~500
IHC~~1:50~100
FC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
QCR8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

QCR8 Antibody (C-term) - Protein Information

Name UQCRQ
Function
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone
Cellular Location
Mitochondrion inner membrane.

QCR8 Antibody (C-term) - Related products

AP10227b: QCR8 Antibody (C-term)

DC00647: Human UQCRQ cDNA Clone

LY13501a: UQCRQ Over-expression Lysate

BP10227b: QCR8 Antibody (C-term) Blocking peptide

QCR8 Antibody (C-term) - Application data

  • QCR8 Antibody (C-term) (Cat. #AP10227b) western blot analysis in WiDr cell line lysates (15ug/lane).This demonstrates the QCR8 antibody detected QCR8 protein (arrow).

  • QCR8 Antibody (C-term) (Cat. #AP10227b) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the QCR8 antibody detected QCR8 protein (arrow).

  • QCR8 Antibody (C-term) (Cat. #AP10227b) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the QCR8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

  • QCR8 Antibody (C-term) (Cat. #AP10227b) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

QCR8 Antibody (C-term) - Research Areas

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BACKGROUND

This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain.

REFERENCES

Barel, O., et al. Am. J. Hum. Genet. 82(5):1211-1216(2008) Wen, J.J., et al. Free Radic. Biol. Med. 37(12):2072-2081(2004) Schagger, H., et al. Meth. Enzymol. 260, 82-96 (1995) : Usui, S., et al. Biochemistry 29(19):4618-4626(1990)