CAMK2N1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q7Z7J9 |
Other Accession | Q9JI15, Q6QWF9, A7MBG3, NP_061054.2 |
Reactivity | Human, Mouse |
Predicted | Bovine, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 8553 Da |
Antigen Region | 37-65 aa |
Gene ID | 55450 |
---|---|
Other Names | Calcium/calmodulin-dependent protein kinase II inhibitor 1, CaMKII inhibitory protein alpha, CaMKIIN-alpha, CAMK2N1 |
Target/Specificity | This CAMK2N1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the C-terminal region of human CAMK2N1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CAMK2N1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CAMK2N1 |
---|---|
Function | Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity). Plays a role in the maintenance of long-term retrieval- induced memory in response to contextual fear (By similarity). Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity in addition to regulation of left ventricular mass (By similarity). Mediates the NLRP3 inflammasome in cardiomyocytes via acting as an inhibitor of the MAPK14/p38 and MAPK8/JNK pathways, thereby regulating ventricular remodeling and cardiac rhythm post- myocardial infarction (By similarity). Negatively effects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (By similarity). |
Cellular Location | Synapse {ECO:0000250|UniProtKB:Q6QWF9}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9JI15}. Postsynaptic density {ECO:0000250|UniProtKB:Q6QWF9} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Wang, C., et al. J. Biol. Chem. 283(17):11565-11574(2008)
Meng, F., et al. Brain Res. 967 (1-2), 161-169 (2003) :
Sedelnikova, A., et al. Int. J. Dev. Neurosci. 20 (3-5), 237-246 (2002) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.