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DYNLRB2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q8TF09 |
| Other Accession | Q9DAJ5, Q32P85, NP_570967.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 10855 Da |
| Antigen Region | 49-77 aa |
| Gene ID | 83657 |
|---|---|
| Other Names | Dynein light chain roadblock-type 2, Dynein light chain 2B, cytoplasmic, Roadblock domain-containing protein 2, DYNLRB2, DNCL2B, DNLC2B, ROBLD2 |
| Target/Specificity | This DYNLRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the Central region of human DYNLRB2. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DYNLRB2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DYNLRB2 |
|---|---|
| Synonyms | DNCL2B, DNLC2B, ROBLD2 |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
| Cellular Location | Cytoplasm, cytoskeleton. |
| Tissue Location | High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
Jin, Q., et al. J. Cell. Physiol. 221(3):707-715(2009)
Meyre, D., et al. Nat. Genet. 41(2):157-159(2009)
Pfister, K.K., et al. J. Cell Biol. 171(3):411-413(2005)
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$ 365.00
$ 140.00
Cat# AP10258C
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