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LUZP4 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LUZP4 Antibody (N-term) AP10265a
    LUZP4 Antibody (N-term) (Cat. #AP10265a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the LUZP4 antibody detected the LUZP4 protein (arrow).
    detail
  • IHC-P - LUZP4 Antibody (N-term) AP10265a
    LUZP4 antibody(N-term) (Cat. #AP10265a) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LUZP4 antibody(N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q9P127
Other Accession NP_057467.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35937 Da
Antigen Region 33-62 aa
Additional Information
Gene ID 51213
Other Names Leucine zipper protein 4, Cancer/testis antigen 28, CT-28, CT28, Tumor antigen HOM-TES-85, LUZP4
Target/Specificity This LUZP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human LUZP4.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLUZP4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LUZP4
Function Export adapter involved in mRNA nuclear export in cancer cells. Binds and enhances the RNA-binding activity of the nuclear RNA export factor NXF1. Can restore mRNA export function in cells compromised by loss of mRNA export adapters (PubMed:25662211).
Cellular Location Nucleus. Cytoplasm Note=In nuclear speckles. Relocalizes to the cytoplasm during cell division.
Tissue Location Expressed specifically in testis. Also expressed in a wide variety of cancer types, but particularly high levels of expression observed in melanoma cells.
Research Areas
Citations (0)
citation

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References

Tureci, O., et al. Oncogene 21(24):3879-3888(2002)
Sahin, U., et al. Clin. Cancer Res. 6(10):3916-3922(2000)

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$ 365.00
$ 140.00
Cat# AP10265a
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