C12orf30 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q14CX7 |
Other Accession | NP_079229.2 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 112292 Da |
Antigen Region | 720-748 aa |
Gene ID | 80018 |
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Other Names | N-alpha-acetyltransferase 25, NatB auxiliary subunit, Mitochondrial distribution and morphology protein 20, N-terminal acetyltransferase B complex subunit MDM20, NatB complex subunit MDM20, N-terminal acetyltransferase B complex subunit NAA25, p120, NAA25, C12orf30, MDM20, NAP1 |
Target/Specificity | This C12orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-748 amino acids from the Central region of human C12orf30. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | C12orf30 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NAA25 |
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Synonyms | C12orf30, MDM20, NAP1 |
Function | Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. May play a role in normal cell-cycle progression. |
Cellular Location | Cytoplasm. |
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the auxiliary subunit of the heteromeric N-terminal acetyltransferase B complex. This complex acetylates methionine residues that are followed by acidic or asparagine residues.
References
Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
Pierce, B.L., et al. Hum. Hered. 69(3):193-201(2010)
Douroudis, K., et al. BMC Med. Genet. 11, 11 (2010) :
Prahalad, S., et al. Arthritis Rheum. 60(7):2124-2130(2009)
Polevoda, B., et al. BMC Proc 3 SUPPL 6, S2 (2009) :
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