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BRMS1L Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q5PSV4 |
| Other Accession | Q3U1T3, A4FV29, NP_115728.2 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37629 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 84312 |
|---|---|
| Other Names | Breast cancer metastasis-suppressor 1-like protein, BRMS1-homolog protein p40, BRMS1-like protein p40, BRMS1L |
| Target/Specificity | This BRMS1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BRMS1L. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BRMS1L Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BRMS1L |
|---|---|
| Function | Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene shows sequence similarity to the human breast carcinoma metastasis suppressor (BRMS1) protein and the mammalian Sds3 (suppressor of defective silencing 3) proteins. This protein is a component of the mSin3a family of histone deacetylase complexes (HDAC).
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Nikolaev, A.Y., et al. Biochem. Biophys. Res. Commun. 323(4):1216-1222(2004)
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