|Application ||WB, E|
|Other Accession||NP_001002006.1, NP_150278.2|
|Calculated MW||68804 Da|
|Antigen Region||3-32 aa|
|Other Names||Cytosolic 5'-nucleotidase 1B, cN1B, Autoimmune infertility-related protein, Cytosolic 5'-nucleotidase IB, cN-IB, NT5C1B, AIRP|
|Target/Specificity||This NT5C1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human NT5C1B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NT5C1B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity).|
|Tissue Location||Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.|
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Provided below are standard protocols that you may find useful for product applications.
Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM].
Gass, N., et al. J Affect Disord 126 (1-2), 134-139 (2010) :
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Sala-Newby, G.B., et al. Biochim. Biophys. Acta 1521 (1-3), 12-18 (2001) :
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