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NT5C1B Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96P26 |
| Other Accession | NP_001002006.1, NP_150278.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 68804 Da |
| Antigen Region | 3-32 aa |
| Gene ID | 100526794;93034 |
|---|---|
| Other Names | Cytosolic 5'-nucleotidase 1B, cN1B, Autoimmune infertility-related protein, Cytosolic 5'-nucleotidase IB, cN-IB, NT5C1B, AIRP |
| Target/Specificity | This NT5C1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human NT5C1B. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NT5C1B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NT5C1B |
|---|---|
| Synonyms | AIRP |
| Function | Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, AMP is the major substrate. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9BXI3}. |
| Tissue Location | Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM].
References
Gass, N., et al. J Affect Disord 126 (1-2), 134-139 (2010) :
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Sala-Newby, G.B., et al. Biochim. Biophys. Acta 1521 (1-3), 12-18 (2001) :
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