KCNT2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q6UVM3 |
Other Accession | NP_940905.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 130501 Da |
Antigen Region | 1069-1097 aa |
Gene ID | 343450 |
---|---|
Other Names | Potassium channel subfamily T member 2, Sequence like an intermediate conductance potassium channel subunit, Sodium and chloride-activated ATP-sensitive potassium channel Slo21, KCNT2, SLICK |
Target/Specificity | This KCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1069-1097 amino acids from the C-terminal region of human KCNT2. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KCNT2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KCNT2 |
---|---|
Synonyms | SLICK |
Function | Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels (PubMed:14684870, PubMed:16687497, PubMed:29069600). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:16687497) (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 (PubMed:16687497). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
Santi, C.M., et al. J. Neurosci. 26(19):5059-5068(2006)
Wei, A.D., et al. Pharmacol. Rev. 57(4):463-472(2005)
Bhattacharjee, A., et al. J. Neurosci. 23(37):11681-11691(2003)
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