DTWD2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8NBA8 |
Other Accession | Q4R7M4, NP_775937.1 |
Reactivity | Human, Mouse |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33416 Da |
Antigen Region | 109-138 aa |
Gene ID | 285605 |
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Other Names | DTW domain-containing protein 2, DTWD2 |
Target/Specificity | This DTWD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human DTWD2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DTWD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DTWD2 {ECO:0000303|PubMed:31804502, ECO:0000312|HGNC:HGNC:19334} |
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Function | Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20a in the D-loop of several cytoplasmic tRNAs (acp3U(20a)) (PubMed:31804502). Also has a weak activity to form acp3U at position 20 in the D-loop of tRNAs (acp3U(20)) (PubMed:31804502). |
Cellular Location | [Isoform 1]: Cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
References
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Manrow, R.E., et al. Genomics 13(2):319-331(1992)
Eschenfeldt, W.H., et al. J. Biol. Chem. 264(13):7546-7555(1989)
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