LMOD2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q6P5Q4 |
Other Accession | A1A5Q0, Q3UHZ5, NP_997046.1 |
Reactivity | Human, Mouse |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 61675 Da |
Antigen Region | 60-88 aa |
Gene ID | 442721 |
---|---|
Other Names | Leiomodin-2, Cardiac leiomodin, C-LMOD, LMOD2 |
Target/Specificity | This LMOD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human LMOD2. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LMOD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LMOD2 |
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Function | Mediates nucleation of actin filaments and thereby promotes actin polymerization (PubMed:18403713, PubMed:26370058, PubMed:25250574, PubMed:26417072). Plays a role in the regulation of actin filament length (By similarity). Required for normal sarcomere organization in the heart, and for normal heart function (PubMed:18403713). |
Cellular Location | Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytoskeleton. Note=Colocalizes with actin filaments in sarcomeres. Detected close to the M line |
Tissue Location | Specifically expressed in heart and skeletal muscles, with higher levels in heart (at protein level). Not expressed in other tissues. |
Provided below are standard protocols that you may find useful for product applications.
References
Chereau, D., et al. Science 320(5873):239-243(2008)
Lane, H.Y., et al. J Clin Psychopharmacol 26(2):128-134(2006)
Conley, C.A., et al. Genomics 73(2):127-139(2001)
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