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LMOD2 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LMOD2 Antibody  (N-term) AP10364a
    LMOD2 Antibody (N-term) (Cat. #AP10364a) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the LMOD2 antibody detected the LMOD2 protein (arrow).
    detail
  • IHC-P - LMOD2 Antibody  (N-term) AP10364a
    LMOD2 antibody (N-term) (Cat. #AP10364a) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LMOD2 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
  • CITATIONS: 1
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q6P5Q4
Other Accession A1A5Q0, Q3UHZ5, NP_997046.1
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 61675 Da
Antigen Region 60-88 aa
Additional Information
Gene ID 442721
Other Names Leiomodin-2, Cardiac leiomodin, C-LMOD, LMOD2
Target/Specificity This LMOD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human LMOD2.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLMOD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LMOD2
Function Mediates nucleation of actin filaments and thereby promotes actin polymerization (PubMed:18403713, PubMed:26370058, PubMed:25250574, PubMed:26417072). Plays a role in the regulation of actin filament length (By similarity). Required for normal sarcomere organization in the heart, and for normal heart function (PubMed:18403713).
Cellular Location Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytoskeleton. Note=Colocalizes with actin filaments in sarcomeres. Detected close to the M line
Tissue Location Specifically expressed in heart and skeletal muscles, with higher levels in heart (at protein level). Not expressed in other tissues.
Research Areas
Citations ( 0 )

References

Chereau, D., et al. Science 320(5873):239-243(2008)
Lane, H.Y., et al. J Clin Psychopharmacol 26(2):128-134(2006)
Conley, C.A., et al. Genomics 73(2):127-139(2001)

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$ 365.00
$ 140.00
Cat# AP10364a
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