|Application ||WB, IHC-P, FC, E|
|Calculated MW||12050 Da|
|Antigen Region||66-94 aa|
|Other Names||WAP four-disulfide core domain protein 12, Putative protease inhibitor WAP12, Whey acidic protein 2, WFDC12, C20orf122, WAP2|
|Target/Specificity||This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human WFDC12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||WFDC12 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Antibacterial protein. Putative acid-stable proteinase inhibitor.|
|Tissue Location||Highly expressed in prostate, skin, lung and esophagus. Weakly expressed in skeletal muscle, epididymis, kidney, trachea, salivary gland, testis and seminal vesicle|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Clauss, A., et al. Biochem. Biophys. Res. Commun. 333(2):383-389(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Clauss, A., et al. Biochem. J. 368 (PT 1), 233-242 (2002) :
Lundwall, A., et al. Biochem. Biophys. Res. Commun. 290(1):452-456(2002)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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