|Application ||WB, E|
|Calculated MW||52387 Da|
|Antigen Region||370-398 aa|
|Other Names||Tubulointerstitial nephritis antigen-like, Glucocorticoid-inducible protein 5, Oxidized LDL-responsive gene 2 protein, OLRG-2, Tubulointerstitial nephritis antigen-related protein, TIN Ag-related protein, TIN-Ag-RP, TINAGL1, GIS5, LCN7, OLRG2, TINAGL|
|Target/Specificity||This TINAGL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-398 amino acids from the C-terminal region of human TINAGL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TINAGL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GIS5, LCN7, OLRG2, TINAGL|
|Function||May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein (By similarity).|
|Tissue Location||Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line. Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly expressed in colon, small intestine, ovary, spleen, testis and prostate. Predominantly found in vascular smooth muscle cells, but also in cardiac and skeletal muscle cells as well as kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Jiang, L.Q., et al. Hypertens. Res. 25(4):647-652(2002)
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