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SAR1B Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - SAR1B Antibody (Center) AP10397c
    SAR1B antibody (Center) (Cat. #AP10397c) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAR1B antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • WB - SAR1B Antibody (Center) AP10397c
    SAR1B Antibody (Center) (Cat. #AP10397c) western blot analysis in MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SAR1B antibody detected the SAR1B protein (arrow).
  • FC - SAR1B Antibody (Center) AP10397c
    SAR1B Antibody (Center) (Cat. #AP10397c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y6B6
Other Accession Q5HZY2, Q5PYH3, Q9CQC9, Q9QVY3, Q3T0T7, NP_057187.1, NP_001028675.1
Reactivity Human
Predicted Bovine, Hamster, Mouse, Pig, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 22410 Da
Antigen Region 89-116 aa
Additional Information
Gene ID 51128
Other Names GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB
Target/Specificity This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.
Dilution IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSAR1B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SAR1B
Synonyms SARA2, SARB
Function Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.
Tissue Location Expressed in many tissues including small intestine, liver, muscle and brain
Research Areas
Citations (0)

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The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.


Cefalu, A.B., et al. Metab. Clin. Exp. 59(4):463-467(2010)
Silvain, M., et al. Clin. Genet. 74(6):546-552(2008)
Charcosset, M., et al. Mol. Genet. Metab. 93(1):74-84(2008)
Jardim, D.L., et al. J. Biochem. Mol. Biol. 38(3):328-333(2005)
Jones, B., et al. Nat. Genet. 34(1):29-31(2003)

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$ 295.00
$ 99.00
Cat# AP10397c
(40 western blots)
Availability: In Stock
Bulk Size
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