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>   home   >   Products   >   Primary Antibodies   >   LCOR Antibody (C-term)   

LCOR Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LCOR Antibody (C-term) AP10400b
    LCOR Antibody (C-term) (Cat. #AP10400b) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the LCOR antibody detected the LCOR protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96JN0
Other Accession Q6ZPI3, NP_115816.2, NP_001164237.1, NP_001164236.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47007 Da
Antigen Region 322-350 aa
Additional Information
Gene ID 84458
Other Names Ligand-dependent corepressor, LCoR, Mblk1-related protein 2, LCOR, KIAA1795, MLR2
Target/Specificity This LCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human LCOR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLCOR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1795, MLR2
Function May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00320, ECO:0000269|PubMed:12535528}
Tissue Location Ubiquitous..
Citations (0)

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LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Palijan, A., et al. J. Biol. Chem. 284(44):30275-30287(2009)
Palijan, A., et al. J. Biol. Chem. 284(44):30264-30274(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Deloukas, P., et al. Nature 429(6990):375-381(2004)

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Cat# AP10400b
(40 western blots)
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