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RASF6 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP10404b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP10404b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
RASF6 Antibody (C-term) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | Q6ZTQ3 |
| Other Accession | NP_803876.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 43384 Da |
RASF6 Antibody (C-term) - Additional info | |
| Gene ID 166824 | |
| Other Names RASSF6; Ras association domain-containing protein 6 | |
| Target/Specificity This RASF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-358 amino acids from the C-terminal region of human RASF6. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RASF6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RASF6 Antibody (C-term) - Protein Information | |
| Name RASSF6 | |
| Function Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity) | |
| Tissue Location Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart | |
RASF6 Antibody (C-term) - Related products
AP10404b: RASF6 Antibody (C-term)
RASF6 Antibody (C-term) - Application data
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RASF6 Antibody (C-term) (Cat. #AP10404b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RASF6 antibody detected the RASF6 protein (arrow).
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RASF6 antibody (C-term) (Cat. #AP10404b) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RASF6 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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RASF6 Antibody (C-term) (Cat. #AP10404b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
RASF6 Antibody (C-term) - Research Areas
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BACKGROUND
RASSF6 is a member of the RAS association (RA) domain family of RAS effectors/tumor suppressors that mediate some of the growth inhibitory properties of RAS (see HRAS; MIM 190020) oncogenes (Eckfeld et al., 2004 [PubMed 15574778]).[supplied by OMIM].
REFERENCES
Ikeda, M., et al. Sci Signal 2 (90), RA59 (2009) : Hesson, L.B., et al. Mol. Cancer 8, 42 (2009) : Hillian, A.D., et al. Genes Immun. 9(6):501-508(2008) Allen, N.P., et al. Oncogene 26(42):6203-6211(2007) Ikeda, M., et al. Exp. Cell Res. 313(7):1484-1495(2007)
