|Application ||FC, WB, E|
|Calculated MW||55499 Da|
|Antigen Region||443-471 aa|
|Other Names||Paired box protein Pax-1, HuP48, PAX1, HUP48|
|Target/Specificity||This PAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-471 amino acids from the C-terminal region of human PAX1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The PAX genes, including PAX1, are a highly conserved family of developmental control genes that encode transcription factors and have been shown to play a role in pattern formation during embryogenesis in vertebrates (McGaughran et al., 2003 [PubMed 12774041]). See PAX7 (MIM 167410) for a discussion of paired box domain genes.
Huang, T.H., et al. Int. J. Gynecol. Cancer 20(4):513-519(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Hillmer, A.M., et al. Nat. Genet. 40(11):1279-1281(2008)
Richards, J.B., et al. Nat. Genet. 40(11):1282-1284(2008)
Fei, Q., et al. Zhonghua Yi Xue Za Zhi 88(37):2597-2602(2008)
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