|Application ||WB, IF, E|
|Other Accession||P30543, Q60613, NP_000666.2|
|Calculated MW||44707 Da|
|Antigen Region||273-301 aa|
|Other Names||Adenosine receptor A2a, ADORA2A, ADORA2|
|Target/Specificity||This ADORA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the Central region of human ADORA2A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ADORA2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
ADORA2A is a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. This protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
Buira, S.P., et al. J. Neurochem. 115(1):283-295(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rogers, P.J., et al. Neuropsychopharmacology 35(9):1973-1983(2010)
Tebano, M.T., et al. ScientificWorldJournal 10, 1768-1782 (2010) :
Kobayashi, H., et al. Behav Brain Funct 6, 50 (2010) :
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