|Application ||WB, IHC-P, E|
|Other Accession||Q5U458, Q2NL21, NP_060668.2|
|Calculated MW||63278 Da|
|Antigen Region||27-56 aa|
|Other Names||DnaJ homolog subfamily C member 11, DNAJC11|
|Target/Specificity||This DNAJC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-56 amino acids from the N-terminal region of human DNAJC11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNAJC11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex.|
|Cellular Location||Mitochondrion. Note=Isoforms show differential submitochondrial localization. A 57 kDa form (potentially isoform 3) shows either mitochondrial matrix or innermembrane (IM) localization, possibly anchored to the IM facing the matrix. A 35 kDa form behaved either as an inner membrane space (IMS) or an IM protein exposed to the IMS|
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Provided below are standard protocols that you may find useful for product applications.
Belongs to the DNAJC11 family. Three named isoforms produced by alternative splicing.
Kneissl, J., et al. Plant Cell 21(10):3212-3225(2009)
Xie, J., et al. FEBS Lett. 581(18):3545-3549(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Henrich, K.O., et al. Eur. J. Cancer 43(3):607-616(2007)
Katoh, M., et al. Int. J. Oncol. 23(4):1219-1224(2003)
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