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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PRSS3 Antibody (N-term)   

PRSS3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRSS3 Antibody (N-term) AP10489a
    PRSS3 Antibody (N-term) (Cat. #AP10489a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PRSS3 antibody detected the PRSS3 protein (arrow).
  • IHC-P - PRSS3 Antibody (N-term) AP10489a
    PRSS3 antibody (N-term) (Cat. #AP10489a) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRSS3 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PRSS3 Antibody (N-term) AP10489a
    PRSS3 Antibody (N-term) (Cat. #AP10489a) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35030-1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 13-40 aa
Additional Information
Other Names Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV, PRSS3, PRSS4, TRY3, TRY4
Target/Specificity This PRSS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human PRSS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRSS3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas
Citations (0)

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PRSS3 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. PRSS3 is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.


Jiang, G., et al. Gut 59(11):1535-1544(2010)
Nakanishi, J., et al. J. Invest. Dermatol. 130(4):944-952(2010)
Salameh, M.A., et al. J. Biol. Chem. 285(3):1939-1949(2010)
Rosendahl, J., et al. Pancreatology 10 (2-3), 243-249 (2010) :
Koistinen, H., et al. Neuroscience 160(1):97-102(2009)

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Cat# AP10489a
(40 western blots)
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