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ST7 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q9NRC1 |
| Other Accession | Q2IBD0, Q09YN2, Q2QLD7, Q99M96, Q2PG42, Q1RLU8, A0M8U1, A4D7R9, NP_060882.2, Q2QLA6, Q09YI5 |
| Reactivity | Rat |
| Predicted | Bovine, Chicken, Zebrafish, Horse, Monkey, Mouse, Pig, Rabbit, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 67166 Da |
| Antigen Region | 169-197 aa |
| Gene ID | 7982 |
|---|---|
| Other Names | Suppressor of tumorigenicity 7 protein, Protein FAM4A1, Protein HELG, ST7, FAM4A1, HELG, RAY1 |
| Target/Specificity | This ST7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human ST7. |
| Dilution | WB~~1:8000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ST7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ST7 |
|---|---|
| Synonyms | FAM4A1, HELG, RAY1 |
| Function | May act as a tumor suppressor. |
| Cellular Location | Membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitously expressed, with highest levels in heart, liver and pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described.
References
Bailey, S.D., et al. Diabetes Care (2010) In press : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009) de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
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