|Application ||WB, E|
|Calculated MW||26971 Da|
|Antigen Region||1-30 aa|
|Other Names||Protein lifeguard 4, Golgi anti-apoptotic protein, Protein S1R, Transmembrane BAX inhibitor motif-containing protein 4, Z-protein, TMBIM4, GAAP, LFG4|
|Target/Specificity||This TMBIM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TMBIM4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMBIM4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release.|
|Cellular Location||Golgi apparatus membrane; Multi- pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
de Mattia, F., et al. Mol. Biol. Cell 20(16):3638-3645(2009)
Zhou, J., et al. Comput Biol Chem 32(3):159-162(2008)
Gubser, C., et al. PLoS Pathog. 3 (2), E17 (2007) :
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Hu, R.M., et al. Proc. Natl. Acad. Sci. U.S.A. 97(17):9543-9548(2000)
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