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CB018 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # SizeAvailability Available Date  
AP10502c 400 µl
(40 western blots)
Backorder 4 months
AP10502c-ev 80 µl
(8 western blots)
Backorder 4 months
  • Specification
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CB018 Antibody (C-term) - Product info

Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, FC
Primary AccessionQ8N357
Other AccessionNP_060347.2
ReactivityHuman
Isotype Rabbit Ig
Calculated MW 40214 Da

CB018 Antibody (C-term) - Additional info

Gene ID 54978
Other Names
C2orf18; Transmembrane protein C2orf18
Target/Specificity
This CB018 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of human CB018.
Dilution
WB~~1:1000
IHC~~1:50~100
FC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
CB018 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

CB018 Antibody (C-term) - Protein Information

Name SLC35F6
Synonyms C2orf18
Function
Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter.
Cellular Location
Mitochondrion. Lysosome membrane; Multi-pass membrane protein
Tissue Location
Expressed in pancreatic ductal adenocarcinoma (PDAC) (at protein level). Strongly expressed in prostate and thyroid. Weakly expressed in lung, heart, liver and kidney

CB018 Antibody (C-term) - Related products

BP10502c: CB018 Antibody (C-term) Blocking Peptide

CB018 Antibody (C-term) - Research Areas

Application data

  • WB - CB018 Antibody (C-term) AP10502c

    CB018 Antibody (C-term) (Cat. #AP10502c) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CB018 antibody detected the CB018 protein (arrow).

  • IHC - CB018 Antibody (C-term) AP10502c

    CB018 antibody (C-term) (Cat. #AP10502c) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CB018 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

  • FC - CB018 Antibody (C-term) AP10502c

    CB018 Antibody (C-term) (Cat. #AP10502c) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

  • WB - CB018 Antibody (C-term) AP10502c
  • IHC - CB018 Antibody (C-term) AP10502c
  • FC - CB018 Antibody (C-term) AP10502c

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BACKGROUND

The exact function of C2orf18 remains unknown. It contains 1 DUF6 domain.

REFERENCES

Kashiwaya, K., et al. Cancer Sci. 100(3):457-464(2009)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)