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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   CB018 Antibody (C-term)   

CB018 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CB018 Antibody (C-term) AP10502c
    CB018 Antibody (C-term) (Cat. #AP10502c) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CB018 antibody detected the CB018 protein (arrow).
  • IHC - CB018 Antibody (C-term) AP10502c
    CB018 antibody (C-term) (Cat. #AP10502c) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CB018 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - CB018 Antibody (C-term) AP10502c
    CB018 Antibody (C-term) (Cat. #AP10502c) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product Information
ApplicationFC, WB, IHC, E
Primary AccessionQ8N357
Other AccessionNP_060347.2
ReactivityHuman
HostRabbit
ClonalityPolyclonal
IsotypeRabbit Ig
Calculated MW40214 Da
Antigen Region329-358 aa
Additional Information
Gene ID54978
Other NamesSolute carrier family 35 member F6, ANT2-binding protein, ANT2BP, Transport and Golgi organization 9 homolog, SLC35F6, C2orf18
Target/SpecificityThis CB018 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of human CB018.
DilutionWB~~1:1000
IHC~~1:50~100
FC~~1:10~50
FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Protein Information
NameSLC35F6
SynonymsC2orf18
Function Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter.
Cellular LocationMitochondrion. Lysosome membrane; Multi-pass membrane protein
Tissue LocationExpressed in pancreatic ductal adenocarcinoma (PDAC) (at protein level). Strongly expressed in prostate and thyroid. Weakly expressed in lung, heart, liver and kidney
Research Areas
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Background

The exact function of C2orf18 remains unknown. It contains 1 DUF6 domain.

References

Kashiwaya, K., et al. Cancer Sci. 100(3):457-464(2009)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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Cat# AP10502c
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(40 western blots)
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