|Application ||WB, IHC-P, FC, E|
|Calculated MW||40214 Da|
|Antigen Region||329-358 aa|
|Other Names||Solute carrier family 35 member F6, ANT2-binding protein, ANT2BP, Transport and Golgi organization 9 homolog, SLC35F6, C2orf18|
|Target/Specificity||This CB018 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of human CB018.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CB018 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter.|
|Cellular Location||Mitochondrion. Lysosome membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in pancreatic ductal adenocarcinoma (PDAC) (at protein level). Strongly expressed in prostate and thyroid. Weakly expressed in lung, heart, liver and kidney|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The exact function of C2orf18 remains unknown. It contains 1 DUF6 domain.
Kashiwaya, K., et al. Cancer Sci. 100(3):457-464(2009)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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