- CITATIONS: 0
|Application||FC, WB, IHC, E|
|Calculated MW||40214 Da|
|Antigen Region||329-358 aa|
|Other Names||Solute carrier family 35 member F6, ANT2-binding protein, ANT2BP, Transport and Golgi organization 9 homolog, SLC35F6, C2orf18|
|Target/Specificity||This CB018 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of human CB018.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Function||Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter.|
|Cellular Location||Mitochondrion. Lysosome membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in pancreatic ductal adenocarcinoma (PDAC) (at protein level). Strongly expressed in prostate and thyroid. Weakly expressed in lung, heart, liver and kidney|
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Provided below are standard protocols that you may find useful for product applications.
The exact function of C2orf18 remains unknown. It contains 1 DUF6 domain.
Kashiwaya, K., et al. Cancer Sci. 100(3):457-464(2009)
Stelzl, U., et al. Cell 122(6):957-968(2005)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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