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PGAM2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PGAM2 Antibody (N-term) AP10504a
    PGAM2 Antibody (N-term) (Cat. #AP10504a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PGAM2 antibody detected the PGAM2 protein (arrow).
  • WB - PGAM2 Antibody (N-term) AP10504a
    PGAM2 Antibody (N-term) (Cat. #AP10504a) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the PGAM2 antibody detected the PGAM2 protein (arrow).
  • IHC-P - PGAM2 Antibody (N-term) AP10504a
    PGAM2 antibody (N-term) (Cat. #AP10504a) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PGAM2 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15259
Other Accession NP_000281.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28766 Da
Antigen Region 12-41 aa
Additional Information
Gene ID 5224
Other Names Phosphoglycerate mutase 2, BPG-dependent PGAM 2, Muscle-specific phosphoglycerate mutase, Phosphoglycerate mutase isozyme M, PGAM-M, PGAM2, PGAMM
Target/Specificity This PGAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-41 amino acids from the N-terminal region of human PGAM2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPGAM2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGAM2
Synonyms PGAMM
Function Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC (synthase) and EC (phosphatase), but with a reduced activity.
Tissue Location In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues
Citations (0)

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Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.


Hadjigeorgiou, G.M., et al. Neuromuscul. Disord. 9 (6-7), 399-402 (1999) :
Tsujino, S., et al. Am. J. Hum. Genet. 52(3):472-477(1993)
Castella-Escola, J., et al. Gene 91(2):225-232(1990)
Castella-Escola, J., et al. Hum. Genet. 84(2):210-212(1990)
Tsujino, S., et al. J. Biol. Chem. 264(26):15334-15337(1989)

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$ 295.00
$ 99.00
Cat# AP10504a
(40 western blots)
Availability: In Stock
Bulk Size
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