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CASC4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q6P4E1 |
| Other Accession | Q6P2L7, NP_816929.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49498 Da |
| Antigen Region | 336-365 aa |
| Gene ID | 113201 |
|---|---|
| Other Names | Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4 |
| Target/Specificity | This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CASC4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GOLM2 (HGNC:24892) |
|---|---|
| Synonyms | CASC4 |
| Cellular Location | Membrane; Single-pass type II membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.
References
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Sato, T., et al. Onkologie 26(3):268-271(2003)
Scheer, M., et al. Mund Kiefer Gesichtschir 7(3):138-145(2003)
Oh, J.J., et al. Nucleic Acids Res. 27(20):4008-4017(1999)
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