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5HT3E Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP10528c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP10528c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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5HT3E Antibody (Center) - Product info | |
| Application | WB, FC
|
| Primary Accession | A5X5Y0 |
| Other Accession | NP_872395.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 51438 Da |
5HT3E Antibody (Center) - Additional info | |
| Gene ID 285242 | |
| Other Names HTR3E; 5-hydroxytryptamine receptor 3E; Serotonin receptor 3E | |
| Target/Specificity This 5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the Central region of human 5HT3E. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions 5HT3E Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
5HT3E Antibody (Center) - Protein Information | |
| Name HTR3E | |
| Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel | |
| Cellular Location Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A | |
| Tissue Location Expressed in adult colon and intestine. | |
5HT3E Antibody (Center) - Related products
AP10528c: 5HT3E Antibody (Center)
5HT3E Antibody (Center) - Application data
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5HT3E Antibody (Center) (Cat. #AP10528c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the 5HT3E antibody detected the 5HT3E protein (arrow).
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5HT3E Antibody (Center) (Cat. #AP10528c) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
5HT3E Antibody (Center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
REFERENCES
Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010) Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010) Lennertz, L., et al. Eur Neuropsychopharmacol 20(6):414-420(2010) Goecke, T.W., et al. Acta Obstet Gynecol Scand 89(1):7-14(2010) Schuhmacher, A., et al. Pharmacogenet. Genomics 19(11):843-851(2009)
