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5HT3E Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - 5HT3E Antibody  (Center) AP10528c
    5HT3E Antibody (Center) (Cat. #AP10528c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the 5HT3E antibody detected the 5HT3E protein (arrow).
  • FC - 5HT3E Antibody  (Center) AP10528c
    5HT3E Antibody (Center) (Cat. #AP10528c) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession A5X5Y0
Other Accession NP_872395.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51438 Da
Antigen Region 126-154 aa
Additional Information
Gene ID 285242
Other Names 5-hydroxytryptamine receptor 3E, 5-HT3-E, 5-HT3E, Serotonin receptor 3E, HTR3E
Target/Specificity This 5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human 5HT3E.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions5HT3E Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR3E
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Cellular Location Cell membrane; Multi-pass membrane protein Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A
Tissue Location Expressed in adult colon and intestine.
Research Areas
Citations (0)

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The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.


Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010)
Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)
Lennertz, L., et al. Eur Neuropsychopharmacol 20(6):414-420(2010)
Goecke, T.W., et al. Acta Obstet Gynecol Scand 89(1):7-14(2010)
Schuhmacher, A., et al. Pharmacogenet. Genomics 19(11):843-851(2009)

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$ 295.00
$ 99.00
Cat# AP10528c
(40 western blots)
Availability: In Stock
Bulk Size
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