|Application ||WB, IHC-P, E|
|Other Accession||NP_001166130.1, NP_066023.2, NP_001166131.1, NP_001166127.1, NP_001166129.1|
|Calculated MW||96490 Da|
|Antigen Region||604-633 aa|
|Other Names||Lateral signaling target protein 2 homolog, hLst2, Zinc finger FYVE domain-containing protein 28, ZFYVE28, KIAA1643, LST2|
|Target/Specificity||This ZFYVE28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-633 amino acids from the C-terminal region of human ZFYVE28.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZFYVE28 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.|
|Cellular Location||Cytoplasm, cytosol. Early endosome membrane. Note=Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated|
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Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.
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