RASAL3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q86YV0 |
Other Accession | NP_075055.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 111898 Da |
Antigen Region | 947-975 aa |
Gene ID | 64926 |
---|---|
Other Names | RAS protein activator like-3, RASAL3 |
Target/Specificity | This RASAL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 947-975 amino acids from the C-terminal region of human RASAL3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RASAL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RASAL3 |
---|---|
Function | Functions as a Ras GTPase-activating protein. Plays an important role in the expansion and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down- stream ERK signaling pathway. |
Cellular Location | Cytoplasm. Cytoplasm, cell cortex |
Tissue Location | Predominantly expressed in cells of hematopoietic lineages. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May functions as a Ras GTPase-activating protein (By similarity).
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Ota, T., et al. Nat. Genet. 36(1):40-45(2004)
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