|Application ||WB, FC, E|
|Other Accession||NP_001015508.1, NP_037489.1|
|Calculated MW||39556 Da|
|Antigen Region||225-253 aa|
|Other Names||Purine-rich element-binding protein gamma, PURG|
|Target/Specificity||This PURG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the C-terminal region of human PURG.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PURG Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Isoform 1 is expressed in testis and glioblastoma. Isoform 2 is expressed in fetal lung|
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Provided below are standard protocols that you may find useful for product applications.
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. PURG lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene.
Liu, H., et al. Nucleic Acids Res. 30(11):2417-2426(2002)
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