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NGRN Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9NPE2 |
| Other Accession | Q2HJC0, NP_001028260.2 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 32408 Da |
| Antigen Region | 261-290 aa |
| Gene ID | 51335 |
|---|---|
| Other Names | Neugrin, Mesenchymal stem cell protein DSC92, Neurite outgrowth-associated protein, Spinal cord-derived protein FI58G, NGRN, FI58G |
| Target/Specificity | This NGRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-290 amino acids from the C-terminal region of human NGRN. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NGRN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NGRN {ECO:0000303|PubMed:27667664, ECO:0000312|HGNC:HGNC:18077} |
|---|---|
| Function | Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system. |
| Cellular Location | Nucleus. Secreted. Mitochondrion membrane |
| Tissue Location | Expressed at high levels in heart, brain and skeletal muscle. In brain, mainly expressed in neurons rather than glial cells. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
NGRN may be involved in neuronal differentiation.
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$ 182.50
$ 70.00
Cat# AP10635b
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