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CD109 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CD109 Antibody (N-term) AP10639a
    CD109 Antibody (N-term) (Cat. #AP10639a) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CD109 antibody detected the CD109 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6YHK3
Other Accession NP_001153059.1, NP_001153060.1, NP_598000.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 161689 Da
Antigen Region 82-109 aa
Additional Information
Gene ID 135228
Other Names CD109 antigen, 150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, Platelet-specific Gov antigen, p180, r150, CD109, CD109, CPAMD7
Target/Specificity This CD109 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the N-terminal region of human CD109.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD109 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD109
Synonyms CPAMD7
Function Modulates negatively TGFB1 signaling in keratinocytes.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 5 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta
Research Areas
Citations (0)

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CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).


Nie, Y.M., et al. Transfus Med 20(6):376-382(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hagiwara, S., et al. Oncogene 29(15):2181-2191(2010)
Bhatti, F.A., et al. Transfus Med 20(2):78-87(2010)
Raychaudhuri, S., et al. Nat. Genet. 41(12):1313-1318(2009)

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Cat# AP10639a
(40 western blots)
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