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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q58A44 |
| Other Accession | NP_001014442.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Antigen Region | 14-42 aa |
| Other Names | Prostate collagen triple helix protein, C1QTNF9B antisense RNA 1, C1QTNF9B antisense gene protein 1, C1QTNF9B-AS1, PCOTH |
|---|---|
| Target/Specificity | This PCOTH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the Central region of human PCOTH. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PCOTH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PCOTH |
|---|---|
| Synonyms | C1QTNF9B-AS1 |
| Function | May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in prostate and testis. Weakly or not expressed in other tissues. Overexpressed in prostate cancers EMBL; BC015452; -; NOT_ANNOTATED_CDS; mRNA EMBL; AB113650; BAD93185.1; -; mRNA RefSeq; NP_001014442.2; NM_001014442.3 RefSeq; NP_001335042.1; NM_001348113.1 RefSeq; NP_001335043.1; NM_001348114.1 UniGene; Hs.642624; - ProteinModelPortal; Q58A44; - BioGrid; 139079; 1 IntAct; Q58A44; 1 STRING; 9606.ENSP00000396192; - BioMuta; PCOTH; - PaxDb; Q58A44; - PRIDE; Q58A44; - ProteomicsDB; 62603; - GeneID; 542767; - KEGG; hsa:542767; - CTD; 542767; - DisGeNET; 542767; - GeneCards; PCOTH; - HGNC; HGNC:39839; PCOTH neXtProt; NX_Q58A44; - eggNOG; ENOG410JCC7; Eukaryota eggNOG; ENOG41114ZV; LUCA HOGENOM; HOG000169380; - InParanoid; Q58A44; - PhylomeDB; Q58A44; - GenomeRNAi; 542767; - PRO; PR:Q58A44; - Proteomes; UP000005640; Unplaced GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell 1: Evidence at protein level; Complete proteome; Cytoplasm; Reference proteome CHAIN 1 107 Prostate collagen triple helix protein /FTId=PRO_0000337141 COMPBIAS 35 107 Pro-rich SEQUENCE 107 AA; 10968 MW; B738A5D9E95AF097 CRC64; MWILSNLMGT SEEGNLLSTV SPTVKALFGK TRVSPIFPFS PRSPFQPLIP RTPGSPWGPV GPASPLGPGF PIGPMGPGKP VGPKGPMLPL GPSGPVGPTS PLFPFCP |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway.
References
Anazawa, Y., et al. Cancer Res. 65(11):4578-4586(2005)
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Cat# AP10641c
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