Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.PCOTH Antibody (Center)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q58A44 |
| Other Accession | NP_001014442.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Antigen Region | 14-42 aa |
| Other Names | Prostate collagen triple helix protein, C1QTNF9B antisense RNA 1, C1QTNF9B antisense gene protein 1, C1QTNF9B-AS1, PCOTH |
|---|---|
| Target/Specificity | This PCOTH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the Central region of human PCOTH. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PCOTH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | C1QTNF9B-AS1 |
|---|---|
| Synonyms | PCOTH |
| Function | May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in prostate and testis. Weakly or not expressed in other tissues. Overexpressed in prostate cancers EMBL; BC015452; -; NOT_ANNOTATED_CDS; mRNA EMBL; AB113650; BAD93185.1; -; mRNA RefSeq; NP_001014442.2; NM_001014442.2 UniGene; Hs.642624; - ProteinModelPortal; Q58A44; - BioGrid; 139079; 1 IntAct; Q58A44; 1 STRING; 9606.ENSP00000396192; - BioMuta; PCOTH; - PaxDb; Q58A44; - PRIDE; Q58A44; - GeneID; 542767; - KEGG; hsa:542767; - CTD; 542767; - DisGeNET; 542767; - GeneCards; C1QTNF9B-AS1; - HGNC; HGNC:39839; C1QTNF9B-AS1 neXtProt; NX_Q58A44; - eggNOG; ENOG410JCC7; Eukaryota eggNOG; ENOG41114ZV; LUCA HOGENOM; HOG000169380; - InParanoid; Q58A44; - PhylomeDB; Q58A44; - BioCyc; ZFISH:G66-31917-MONOMER; - GenomeRNAi; 542767; - PRO; PR:Q58A44; - Proteomes; UP000005640; Unplaced GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell 1: Evidence at protein level; Complete proteome; Cytoplasm; Reference proteome CHAIN 1 107 Prostate collagen triple helix protein /FTId=PRO_0000337141 COMPBIAS 35 107 Pro-rich SEQUENCE 107 AA; 10968 MW; B738A5D9E95AF097 CRC64; MWILSNLMGT SEEGNLLSTV SPTVKALFGK TRVSPIFPFS PRSPFQPLIP RTPGSPWGPV GPASPLGPGF PIGPMGPGKP VGPKGPMLPL GPSGPVGPTS PLFPFCP |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.
info@abgent.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway.
References
Anazawa, Y., et al. Cancer Res. 65(11):4578-4586(2005)
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
$ 295.00
$ 99.00
Cat# AP10641c
Availability: In Stock
Seasonal Special on Bulk Order
Request Quote Here
Request Quote Here
Ordering Information
United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900
Other Products
Shipping Information
Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
