|Application ||WB, IHC-P, FC, E|
|Antigen Region||14-42 aa|
|Other Names||Prostate collagen triple helix protein, C1QTNF9B antisense RNA 1, C1QTNF9B antisense gene protein 1, C1QTNF9B-AS1, PCOTH|
|Target/Specificity||This PCOTH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the Central region of human PCOTH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PCOTH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway.|
|Tissue Location||Expressed in prostate and testis. Weakly or not expressed in other tissues. Overexpressed in prostate cancers EMBL; BC015452; -; NOT_ANNOTATED_CDS; mRNA EMBL; AB113650; BAD93185.1; -; mRNA RefSeq; NP_001014442.2; NM_001014442.3 RefSeq; NP_001335042.1; NM_001348113.1 RefSeq; NP_001335043.1; NM_001348114.1 UniGene; Hs.642624; - ProteinModelPortal; Q58A44; - BioGrid; 139079; 1 IntAct; Q58A44; 1 STRING; 9606.ENSP00000396192; - BioMuta; PCOTH; - PaxDb; Q58A44; - PRIDE; Q58A44; - ProteomicsDB; 62603; - GeneID; 542767; - KEGG; hsa:542767; - CTD; 542767; - DisGeNET; 542767; - GeneCards; PCOTH; - HGNC; HGNC:39839; PCOTH neXtProt; NX_Q58A44; - eggNOG; ENOG410JCC7; Eukaryota eggNOG; ENOG41114ZV; LUCA HOGENOM; HOG000169380; - InParanoid; Q58A44; - PhylomeDB; Q58A44; - GenomeRNAi; 542767; - PRO; PR:Q58A44; - Proteomes; UP000005640; Unplaced GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell 1: Evidence at protein level; Complete proteome; Cytoplasm; Reference proteome CHAIN 1 107 Prostate collagen triple helix protein /FTId=PRO_0000337141 COMPBIAS 35 107 Pro-rich SEQUENCE 107 AA; 10968 MW; B738A5D9E95AF097 CRC64; MWILSNLMGT SEEGNLLSTV SPTVKALFGK TRVSPIFPFS PRSPFQPLIP RTPGSPWGPV GPASPLGPGF PIGPMGPGKP VGPKGPMLPL GPSGPVGPTS PLFPFCP|
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May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway.
Anazawa, Y., et al. Cancer Res. 65(11):4578-4586(2005)
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