|Application ||IHC-P, WB, FC, E|
|Other Accession||Q4R7V1, NP_077817.2|
|Calculated MW||69752 Da|
|Antigen Region||309-338 aa|
|Other Names||Centrosomal protein of 70 kDa, Cep70, p10-binding protein, CEP70, BITE|
|Target/Specificity||This CEP70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-338 amino acids from the Central region of human CEP70.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CEP70 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized at the center of the radial microtubule array in interphase and at the spindle poles during various stages of mitosis|
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Provided below are standard protocols that you may find useful for product applications.
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Lim, J., et al. Cell 125(4):801-814(2006)
Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)
Andersen, J.S., et al. Nature 426(6966):570-574(2003)
Casenghi, M., et al. Dev. Cell 5(1):113-125(2003)
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