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ARV1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, FC, E |
|---|---|
| Primary Accession | Q9H2C2 |
| Other Accession | Q3SZW3, NP_073623.1 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 31052 Da |
| Antigen Region | 23-51 aa |
| Gene ID | 64801 |
|---|---|
| Other Names | Protein ARV1, hARV1, ARV1 |
| Target/Specificity | This ARV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human ARV1. |
| Dilution | WB~~1:2000 IHC-P~~1:50~100 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ARV1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARV1 |
|---|---|
| Function | Plays a role as a mediator in the endoplasmic reticulum (ER) cholesterol and bile acid homeostasis (PubMed:11063737, PubMed:12145310, PubMed:20663892). Participates in sterol transport out of the ER and distribution into plasma membranes (PubMed:20663892). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous. Highly expressed in liver and adipose. |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
May act as a mediator of sterol homeostasis (Potential).
References
Tong, F., et al. J. Biol. Chem. 285(44):33632-33641(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Swain, E., et al. J. Biol. Chem. 277(39):36152-36160(2002)
Tinkelenberg, A.H., et al. J. Biol. Chem. 275(52):40667-40670(2000)
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$ 365.00
$ 140.00
Cat# AP10655a
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