|Application ||FC, WB, IHC-P, E|
|Other Accession||Q3SZW3, NP_073623.1|
|Calculated MW||31052 Da|
|Antigen Region||23-51 aa|
|Other Names||Protein ARV1, hARV1, ARV1|
|Target/Specificity||This ARV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human ARV1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARV1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role as a mediator in the endoplasmic reticulum (ER) cholesterol and bile acid homeostasis (PubMed:11063737, PubMed:12145310, PubMed:20663892). Participates in sterol transport out of the ER and distribution into plasma membranes (PubMed:20663892).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitous. Highly expressed in liver and adipose.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
May act as a mediator of sterol homeostasis (Potential).
Tong, F., et al. J. Biol. Chem. 285(44):33632-33641(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Swain, E., et al. J. Biol. Chem. 277(39):36152-36160(2002)
Tinkelenberg, A.H., et al. J. Biol. Chem. 275(52):40667-40670(2000)
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