|Application ||WB, IHC-P, E|
|Other Accession||Q8CAL5, NP_004457.1|
|Calculated MW||63707 Da|
|Antigen Region||56-84 aa|
|Other Names||Glypican-5, Secreted glypican-5, GPC5|
|Target/Specificity||This GPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human GPC5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPC5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface proteoglycan that bears heparan sulfate.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side|
|Tissue Location||In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq].
Lorentzen, A.R., et al. J. Neuroimmunol. 226 (1-2), 194-197 (2010) :
Landi, M.T., et al. Lancet Oncol. 11(8):714-716(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Li, Y., et al. Lancet Oncol. 11(4):321-330(2010)
Arking, D.E., et al. PLoS ONE 5 (3), E9879 (2010) :
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