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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   B4GALT6 Antibody (C-term)   

B4GALT6 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - B4GALT6 Antibody (C-term) AP10697B
    B4GALT6 Antibody (C-term) (Cat. #AP10697b) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the B4GALT6 antibody detected the B4GALT6 protein (arrow).
  • IHC-P - B4GALT6 Antibody (C-term) AP10697B
    B4GALT6 Antibody (C-term) (Cat. #AP10697b) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the B4GALT6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - B4GALT6 Antibody (C-term) AP10697B
    B4GALT6 Antibody (C-term) (Cat. #AP10697b) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBX8
Other Accession Q9WVK5, NP_004766.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44914 Da
Antigen Region 319-346 aa
Additional Information
Gene ID 9331
Other Names Beta-1, 4-galactosyltransferase 6, Beta-1, 4-GalTase 6, Beta4Gal-T6, b4Gal-T6, 241-, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 6, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 6, Glucosylceramide beta-1, 4-galactosyltransferase, Lactosylceramide synthase, LacCer synthase, UDP-Gal:glucosylceramide beta-1, 4-galactosyltransferase, B4GALT6
Target/Specificity This B4GALT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-346 amino acids from the C-terminal region of human B4GALT6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsB4GALT6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name B4GALT6
Function Required for the biosynthesis of glycosphingolipids.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack
Tissue Location High expression in brain and adrenal gland, lower in liver, lung, colon and peripheral white blood cells
Research Areas
Citations (0)

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This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.


Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009) Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003) Fan, Y., et al. DNA Seq. 13(1):1-8(2002) Amado, M., et al. Biochim. Biophys. Acta 1473(1):35-53(1999) Takizawa, M., et al. Biochim. Biophys. Acta 1438(2):301-304(1999)

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Cat# AP10697B
(40 western blots)
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